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New York: In a ground-breaking discovery, scientists have created 3D techniques that can regenerate lungs from human stem cells.Daniel Weiss, a professor of medicine at the University of Vermont, has developed lung tissue bioengineering technique that involves scaffold - or framework - of lungs from human corpse to engineer new lungs for patients with end-stage lung diseases.They examined several perspectives on the process of stripping the cellular material from these lungs - called decellularising - and replacing it with stem cells (recellularisation) in an effort to grow new, healthy lungs for transplantation."Its expensive and difficult to repopulate an entire human lung at one time. Unlike in mouse models, this does not readily allow the study of multiple conditions, such as cell types, growth factors and environmental influences like mechanical stretch - normal breathing motions - that will all affect successful lung recellularisation," Weiss said.To address this, Darcy Wagner, a post-doctoral fellow working in Weiss lab, developed a technique to dissect out and recellularise multiple, small segments in a manner that would take into consideration the appropriate three-dimensional interaction of blood vessels with the lung's airways and air sacs.With the help of another novel technique - thermography or thermal imaging - Wagner and colleagues developed a non-invasive and non-destructive means for monitoring the lung scaffolds integrity and physiologic attributes in real-time during the decellularisation process.According to Wagner, this method could be used as a first step in evaluating whether lungs and eventual scaffolds are suitable for recellularisation and transplantation.The study appeared in the journal Biomaterials.IANS

Listen up India: Advice Adda's #NotAHypocrite campaign sends a strong message

from firstpost

Listen up India: Advice Adda's #NotAHypocrite campaign sends a strong message

Stereotyping India is becoming a regular affair these days. While a German professor recently denied an internship to an Indian student because his country had a "rape problem", filmmaker Le...


Swine flu death toll climbs to 1731; number of cases touches 30,000-mark across India

from ibn

Swine flu death toll climbs to 1731; number of cases touches 30,000-mark across India

New Delhi: The swine flu toll in the country climbed to 1,731 on Monday as 21 more deaths were reported even as the number of persons affected by the disease inched close to 30,000-mark, surpas...

Medtronics: Technologies that transform lives

from ibn

Medtronics: Technologies that transform lives

In this special episode, Experts from Medtronics discuss the challenges and solutions to improves the India\'s healthcare system. ...

Chronic sleep deprivation can lead to high blood pressure at night: study

from firstpost

Chronic sleep deprivation can lead to high blood pressure at night: study

New York: Chronic sleep deprivation can increase night time blood pressure, putting you at greater risk of heart diseases, warns new research."For the first time, we demonstrated that insufficien...

After Maharashtra, Haryana govt plans bill to ban beef, cow slaughter to be dealt as murder

from firstpost

After Maharashtra, Haryana govt plans bill to ban beef, cow slaughter to be dealt as murder

After Maharastra, the Haryana government is all set introduce a bill in the Budget session to ban beef and cow slaughter in the state, says a report in CNN-IBN. The report adds the government intends ...

Here's how Mumbai's street kids find hope, shelter and education

from firstpost

Here's how Mumbai's street kids find hope, shelter and education

A story by Our Better World telling stories of good to inspire action.<iframe width="854" height="510" src="https://www.youtube.com/embed/hVp4CP1DfyQ" frameborder...

Researchers have identified a natural protection against Alzheimer's

from firstpost

Researchers have identified a natural protection against Alzheimer's

Washington:Researchers have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease (AD).The genetic...