Leonardo Vetra is a physicist who is murdered. His daughter Vittoria (Ayelet Zurer) and symbolist Robert Langdon (Tom Hanks) go on a quest following this. Some clues from the secret brotherhood, The Illuminati, leads the two of them all around The Vatican, including the four altars of science, namely the Earth, Air, Fire and Water. An assassin (Nikolaj Lie Kaas), who works for the brotherhood,...

Leonardo Vetra is a physicist who is murdered. His daughter Vittoria (Ayelet Zurer) and symbolist Robert Langdon (Tom Hanks) go on a quest following this. Some clues from the secret brotherhood, The Illuminati, leads the two of them all around The Vatican, including the four altars of science, namely the Earth, Air, Fire and Water. An assassin (Nikolaj Lie Kaas), who works for the brotherhood, captures four cardinals and murders each one of them in a gruesome way. Will Robert and Vittoria find the new destructive weapon that could kill millions of people in time?