Chev (Jason Statham) is a professional hitman for a crime syndicate. His girlfriend Eve (Amy Smart) has no clue about this and Chev plans to quit his job soon. But the syndicate does not take kindly to this and they get another assassin Ricky Verona (Jose Pablo Cantillo) to inject a slow poison into Chev. A desperate Chev runs through town, keeping his heart-rate up to ensure that the poison does...

Chev (Jason Statham) is a professional hitman for a crime syndicate. His girlfriend Eve (Amy Smart) has no clue about this and Chev plans to quit his job soon. But the syndicate does not take kindly to this and they get another assassin Ricky Verona (Jose Pablo Cantillo) to inject a slow poison into Chev. A desperate Chev runs through town, keeping his heart-rate up to ensure that the poison does not work too fast. He has to keep Eve safe while he flushes out his enemies and kills them. Will he be able to find an antidote amidst all this?