Anthapuram revolves around an ordinary girl, Divya who becomes Rani Mrunalini Devi in due course of time. Divya, illegally born to her mother, rejected by her lover Anand takes a daring decision to become a surrogate mother for a Jamindari family. She grabs the opportunity to become the ruler of the family and attains the status of Rani Mrunalini Devi.