When Danny Tanner's wife dies unexpectedly, he is left with three young daughters, D.J., Stephanie, and Michelle, and no one to help him raise them. In step Jesse Katsopolis and Joey Gladstone, friend of Danny and caring guardians to the girls. Jesse, a rock-'n-roll biker, and Joey, a fun-loving comedian, prove to be terrific role models and parental figures to the girls.